My Malignant Melanoma

Seanty's experiences with Metastatic Malignant Melanoma. Part of Email us direct at

Monday, 21 December 2009


UK Trials of PLX4032 are at Oxbridge

The Oxford Cancer Centre and Addenbrooks in Cambridge are both conducting Phase 1 trials of the PLX4032/RO4987655 "superdrug" for patients with advanced MM.

Thursday, 17 December 2009


"Melanoma Code Cracked"

Just in case you hadn't heard, CRUK have sequenced a complete melanoma genome, and found 33,000 mutations, confirming the "multi-hit" nature of cancer causation. More.

Tuesday, 8 December 2009



A fellow melanoma patient asked me this week about the UK trial of a new anti-melanoma drug, a MEK inhibitor called RO4987655. Here's a clinical trial in the UK of the drug. The drug gave complete remission in an animal study, and side-effects are not too bad. It has a similar mode of action to the PLX4032 drug which is giving such hope. Sounds worth a shot.

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Etienne Callebout

A concerned friend of a melanoma patient has written to me to ask about naturopathy in general and a naturopath called Etienne Callebout in particular. Of course naturopathy is little more than systematised quackery, but let's have a quick look at the things Callebout's publicity says he uses to treat cancer:

Aloe vera-Quackery
Amygdalin (laetrile)- Quackery
Bovine cartilage - Quackery
DMSO - Quackery

- you get the idea.

Wobe-Mugos enzymes - worthless
Glandulars - senseless
Green tea can be a nice drink, but does not cure cancer.
Iscador -is a trade name for mistletoe extract which "has no proven benefit and can cause harm"
Flaxseed oil - extremely questionable
Maitake - extremely questionable
Shark cartilage - Quackery
Homeopathic remedies - there are no such things

A quick glance over the 'net shows that these are just a small selection from Callebout's extensive arsenal of nice little earners. Cancer Patients Beware!

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